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5 Best Alternative Pain Reliefs of 2025

Last Updated - 2025/04/27

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Medistik

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis Muscle & Joint Pain, 58g, Pack of 2

Medistik

CA$43.99

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Main highlights
- THE STRONGEST: MEDISTIK is by far, the strongest non-prescription topical pain reliever available, best alternative to Pain Relief Cream. Our long-lasting extra strength formula is ideal for serious pain management.
- RESTORE: Once applied, MEDISTIK promotes long-term healing by attacking inflammation in your body and providing lasting recovery and deep pain relief you can rely on.
- PRIME: Use MEDISTIK to prime and relax tight muscles for athletic training, peak performances, and day-to-day activities.
- PERFORM: When you’re in pain, use MEDISTIK to attack it directly. A powerful integrated system fights pain and inflammation at the source instead of masking it.
- ALL IN ONE SOLUTION: MEDISTIK works for tight muscles, chronic pain, pulled muscles, arthritis, joint pain, cramps and more. It also works for day-to-day irritations like sore feet, neck pain and headaches!
CA$43.99
2

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

LivRelief

LivRelief Extra Strength Nerve Pain Relief Cream for Cutaneous Pain, Neuralgia, Sciatica Pain & Diabetic Neuropathy - 50g (Pack of 2)

LivRelief

CA$38.49

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Main highlights
- Pack of 2
- LivRelief Nerve Pain Relief Cream provides fast and consistent relief from the agony of nerve pain and allows you to regain control over the life you wish to live.
- LivRelief Nerve Pain Relief Cream delivers the active ingredients quickly and consistently right where you need it.
CA$38.49
3

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Independently published

Alternative Pain Relief: A Pill-Free Tool Kit

Independently published

CA$18.53

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Main highlights
CA$18.53
4

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Medistik

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis, Knee, Muscle & Joint Pain (1)

Medistik

CA$24.95

More Details
Main highlights
- THE STRONGEST: MEDISTIK is by far, the strongest non-prescription topical pain reliever available, best alternative to Pain Relief Cream. Our long-lasting extra strength formula is ideal for serious pain management.
- RESTORE: Once applied, MEDISTIK promotes long-term healing by attacking inflammation in your body and providing lasting recovery and deep pain relief you can rely on.
- PRIME: Use MEDISTIK to prime and relax tight muscles for athletic training, peak performances, and day-to-day activities.
- PERFORM: When you’re in pain, use MEDISTIK to attack it directly. A powerful integrated system fights pain and inflammation at the source instead of masking it.
- ALL IN ONE SOLUTION: MEDISTIK works for tight muscles, chronic pain, back pain relief, arthritis pain relief, joint pain, cramps and more. It also works for day-to-day irritations like sore feet, neck pain relief and headache relief.
CA$24.95
5
Best Value

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Re-up Recovery

Re-Up, Fast Acting Roll-on, Pain Relief for Arthritis, Muscle, and Joint Pain, NSAID-Free Formula, Enhanced Pain Relief, Canadian Company.

Re-up Recovery

CA$19.99

More Details
Main highlights
- RAPID PAIN RELIEF: Re-up Recovery Roll-on is one of the strongest non-prescription topical pain reliever on the market, best alternative to Pain Relief Cream. Our long-lasting extra strength formula is ideal for pain management, with instant results.
- NSAID-FREE FORMULA: Alternative pain relief solution that doesn't contain traditional NSAID medications while still providing effective relief
- KEY INGREDIENTS: MENTHOL - 8%, CAMPHOR 3%, METHYL SALICYLATE, ARNICA MONTANA
- IT WORKS: Re-up Recovery Roll-on provides a strong cooling sensation, and effectively targets multiple types of pain including arthritis discomfort, muscle soreness, and joint inflammation
- COOLING SENSATION: Delivers an immediate cooling effect upon application to help soothe sore areas and provide comfort
- CONVENIENT APPLICATION: Easy-to-use roll-on applicator allows precise, mess-free distribution of the pain-relieving formula
- CANADIAN COMPANY: Created by professional athletes so you know it works!
CA$19.99

5 Best Alternative Pain Reliefs of 2025

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis Muscle & Joint Pain, 58g, Pack of 2

LivRelief Extra Strength Nerve Pain Relief Cream for Cutaneous Pain, Neuralgia, Sciatica Pain & Diabetic Neuropathy - 50g (Pack of 2)

Alternative Pain Relief: A Pill-Free Tool Kit

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis, Knee, Muscle & Joint Pain (1)

Re-Up, Fast Acting Roll-on, Pain Relief for Arthritis, Muscle, and Joint Pain, NSAID-Free Formula, Enhanced Pain Relief, Canadian Company.

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