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5 Best Sinus Medicines of 2025

Last Updated - 2025/04/27

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

NeilMed

NeilMed Sinus Rinse Complete Kit, 50 Count

NeilMed

CA$19.99

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Main highlights
- Suitable for use after sinus surgery and during pregnancy
- Soothing, No Burning or Stinging Large Volume and Low Pressure System for Saline Nasal Irrigation, Moisturization and Daily Nasal Hygiene
- Preservative, Drug, Iodine, BPA, Gluten and Latex Free
- Nasal Allergies, Dryness and Hay Fever, Sinus Pressure and Nasal Stuffiness, Nasal Symptoms from Flu and Cold, Nasal Irritation from Occupational and House Dust, Fumes, Animal Dander, Grass, Pollen, Smoke, etc., Post Nasal Drip and Nasal Congestion
- Excellent cleansing prior to spraying nasal corticosteroids
CA$19.99
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

HydraSense

hydraSense NetiRinse Refill Salt Packets, Universal Pre-Measured Self-Mix Packets, Reduces and Relieves Nasal Cold Symptoms, 60 Count

HydraSense

CA$16.29

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Main highlights
- Effectively reduces and relieves nasal cold symptoms such as nasal obstructions and secretion, Nasal congestion and related sinus pressure
- Does not include any chemical additives, preservatives or iodine
- Contains 60 Pre-Measured 4g Salt Packets
- Can be used universally with other self-mix sinus rinse devices
- Can be used on a daily basis by using one salt packet, or using 2 salt packets daily for specialty nasal care
CA$16.29
3

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol

TYLENOL Sinus Extra Strength eZ Tabs, Relieves Sinus congestion and other Sinus symptoms, Daytime and Nighttime, Convenience Pack, 40ct

Tylenol

CA$12.77

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Main highlights
- Tylenol Sinus Extra Strength Daytime/Nighttime Combo, 24+16 pack, helps relieves your day and night sinus symptoms
- Night tablets also contain 2 mg of Chlorpheniramine Maleate as an antihistamine for runny nose and sneezing
- Get fast, effective relief of symptoms including sinus-related pain and pressure, sinus headache, sinus congestion, aches and pains and runny nose and sneezing (nighttime only) due to the common cold or flu
- For adult uses only (12 years and older). Take 1-2 caplet tablets every 4 hours as needed; Do not exceed a combined total of any 8 caplets in 24 hours
- Each day and night tablet contains 500 mg of Acetaminophen to help relieve pain and reduce fever, 5 mg of Phenylephrine Hydrochloride for nasal decongestion
CA$12.77
4

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol

TYLENOL Extra Strength Sinus eZ Tabs, Relieves Sinus congestion and other sinus Symptoms, Daytime, 40ct

Tylenol

CA$12.77

More Details
Main highlights
- To use, Adults and children 12 years and older, take 1-2 daytime tablets every 4 hours as needed
- Made with 500 mg of Acetaminophen for help relieve pain and reduce fever and 5 mg of Phenylephrine Hydrochloride for nasal decongestion
- Made in an easy-to-swallow tablet form
- Get effective relief of symptoms including nasal congestion, sinus pain and pressure, fever, sore throat, and headache due to the common cold or flu
- 40-count package of Tylenol Sinus Extra Strength Day Time Tablets help relieve your morning sinus symptoms
CA$12.77
5
Best Value

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Boiron

Boiron Sinusalia, 60 Tablets, Homeopathic Medicine for Nasal Congestion and Pain Related to Sinus Inflammation Like Stuffy Nose and Sinus Pressure, Non-Drowsy, For Ages 4 to Adult

Boiron

CA$14.49

More Details
Main highlights
- HOMEOPATHIC MEDICINES: Help keep your family healthy with Boiron's line of cough, cold & flu medicines. Try Coryzalia for relief from sneezing, runny nose & nasal congestion, Oscillococcinum for relief from flu-like symptoms & Stodal for cough relief.
- HOMEOPATHIC MEDICINE FOR THE WHOLE FAMILY: Sinusalia can be used to provide relief from nasal congestion and pain from sinus inflammation by children 4 years of age to adults. Sinusalia tablets dissolve quickly, so they are easy to take without water.
- HOMEOPATHIC MEDICINE FOR SINUS RELIEF: Sinusalia is a homeopathic medicine that relieves congestion & pain due to sinus inflammation, like a stuffy nose, facial pain or pressure. Use this non-drowsy solution to help your family in cold or allergy seasons.
- FOUNDED IN 1932: With a presence in Canada for 30 years, you can rely on Boiron homeopathic medicines for your whole family, from newborns to the elderly. Homeopathic medicines may not be right for everyone, always read and follow the label.
CA$14.49

5 Best Sinus Medicines of 2025

NeilMed Sinus Rinse Complete Kit, 50 Count

hydraSense NetiRinse Refill Salt Packets, Universal Pre-Measured Self-Mix Packets, Reduces and Relieves Nasal Cold Symptoms, 60 Count

TYLENOL Sinus Extra Strength eZ Tabs, Relieves Sinus congestion and other Sinus symptoms, Daytime and Nighttime, Convenience Pack, 40ct

TYLENOL Extra Strength Sinus eZ Tabs, Relieves Sinus congestion and other sinus Symptoms, Daytime, 40ct

Boiron Sinusalia, 60 Tablets, Homeopathic Medicine for Nasal Congestion and Pain Related to Sinus Inflammation Like Stuffy Nose and Sinus Pressure, Non-Drowsy, For Ages 4 to Adult

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